BDBM50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole
SMILES Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
InChI Key InChIKey=CEUORZQYGODEFX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 86 hits for monomerid = 50130293
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]raclopride from human D2 dopamine receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Partial agonist activity at human D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.343nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]spiperone from human D2LR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]spiperone from human D2SR expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membranes after 90 mins by micro beta scintillation c...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 0.520nMAssay Description:Displacement of [3H]spiperone from human D2LR expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Displacement of [3H]spiperone from human D2LR expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 0.687nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by MicroBeta scintillation co...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-raclopride from human dopamine D2L receptor expressed in HEK293 after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-raclopride from human D2LR expressed in HEK293 cell membranes after 1 hr at 37 degC by microbeta counting methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 1.60nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-N-methylspiperone from D2 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scinti...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-N-methylspiperone from D2 receptor (unknown origin) expressed in HEK293T cell membranes measured after 2 hrs by microbeta scinti...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [125I]ABN from human recombinant D2L receptor expressed in HEK cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]methylspiperone from human D2 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-N-methylspiperone from human D2 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in CRL:CD(SD)BR-COBS rat striatum by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Third Tokushima Institute of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 5nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor short form expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Affinity DataKi: 9.70nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair